What is E-Shot™ and How Does it Work?
Erectile dysfunction can have a profound impact on confidence, relationships and overall well-being. While some treatments provide temporary symptom relief, they don’t always address the underlying cause of poor blood flow and tissue health.
At MansMatters, we offer a next-generation E-Shot™ treatment, designed to support natural regeneration and improve erectile function over time. The E-Shot™ harnesses the power of plasma protein derived from whole blood, combined with advanced processing techniques and complementary therapies, to promote vascular health, nerve function and tissue repair.
Unlike standard Growth Factor treatments, E-Shot™ undergoes an enhanced process, ensuring higher platelet concentration, reduced inflammation and superior regenerative potential compared to traditional approaches like the P-Shot™.
The E-Shot™ treatment is an innovative biological therapy that uses growth factor therapy to support erectile function naturally. The process involves:
- Blood collection, where a small sample is drawn and processed to extract plasma protein derived from whole blood.
- Advanced processing, where the plasma protein undergoes photoactivation and high-speed centrifugation to optimise its regenerative properties.
- Targeted application, where the growth factor therapy is carefully administered to specific treatment sites in the penis to enhance tissue repair.
- Complementary therapies, where the treatment is combined with shockwave therapy and Extracorporeal Magnetic Transduction (EMTT) to further support vascular function and cellular repair.
Key Differences Between E-Shot™ and P-Shot™
| Feature | E-Shot | P-Shot/ PRP |
| Platelet Concentration | Up to 1.6 billion platelets per dose | Up to 1 million platelets per dose |
| Red Blood Cells (Inflammatory) | Eliminated to reduce inflammation & enhance healing | May include some Red blood cells |
| White Blood Cells (Regenerative) | Maximised for potential repair and regenerative benefits | Typically not activated |
| White Blood cells (Pro-Inflammatory) | Minimised to reduce inflammation & swelling | Traces remain |
| Pain/discomfort | Small injections for minimal discomfort | 1 larger injection maybe used in multiple locations |
| Risk of infection | Four sterilised needles used at each site to reduce infection risk | Repeated use of the same needle in multiple sites |
| Growth factors (Signals for healing) | 350+ Growth factors | About 6 Growth factors |
Why is the E-Shot™ More Effective?
- Higher platelet concentration delivers more growth factors to the treatment site
- Reduces inflammation by eliminating excess red blood cells that can slow healing
- Maximises regenerative potential with enhanced white blood cells for repair
- More comfortable experience with smaller, more precise injections for minimal discomfort
The E-Shot™ Advantage: More Than
Just Growth Factor Therapy
Unlike standard growth factor treatments, E-Shot™ undergoes an enhanced processing method to maximise its regenerative potential. MansMatters also offers additional therapies that can be used alongside E-Shot™ for a more comprehensive approach to erectile function restoration.
- Advanced Growth Factor Processing – E-Shot™ undergoes a photoactivation technique, which enhances the activity of the growth factors, optimising their regenerative potential.
- Extracorporeal Magnetic Transduction (EMTT) – This therapy is available as a post-injection treatment to support cellular nutrient transfer and tissue healing.
- Shockwave Therapy (Optional Add-On) – Some patients may benefit from shockwave therapy as part of a broader treatment plan to improve blood flow and stimulate vascular regeneration.
This multi-modal approach means that E-Shot™ does more than just growth factor therapy – it works holistically to restore erectile function naturally.
Who Can Benefit from E-Shot™ Treatment?
This treatment is suitable for men who:
- Experience erectile dysfunction, ranging from mild to severe cases
- Have circulatory issues such as diabetes, high blood pressure, or cardiovascular disease
- Struggle with Peyronie’s disease and are looking for tissue regeneration support
- Want to enhance erectile function naturally without medications or implants
- Have tried other treatments but need long-term improvements in blood flow and function
Unlike conventional treatments, E-Shot™ focuses on long-term healing, allowing men to regain natural performance rather than relying on short-term fixes.
What to Expect During Treatment
Personalised Consultation
- A private, one-on-one assessment to discuss your medical history and treatment goals
- A customised treatment plan designed by our expert team
The E-Shot™ Procedure
- A small blood sample is drawn and processed using advanced growth factor techniques
- The growth factor is applied to targeted treatment sites in the penis
- The procedure is quick, minimally invasive and virtually painless
Recovery & Results
- No downtime – patients can return to normal activities immediately
- Improvements develop gradually over the following weeks, as tissue repair progresses
- A full course of treatment typically involves multiple sessions for optimal results
What to Expect in the MansMatters Clinic
We are experts in the field of men’s health. We offer our patients the safest, most advanced and effective men’s health treatments in a comfortable, relaxed and premium environment.
Complimentary Initial
Consultation
This 20 minute consultation with our knowledgeable clinical advisors to assess your goals, initial evaluation of your medical history, and determination of the best approach to achieve the desired outcomes.
Consultation
Pre-Treatment
This involves detailed information on the treatment being undertaken and allows the practitioner to answer any questions you have, as well as providing instructions on preparing for the treatments, including any pre-requisite actions prior to undertaking the treatments.
Treatment
We are committed to solving your men’s health challenges by administering procedures and providing personalised care. Let us guide you with confidence and comfort at every step of your journey, reclaiming the best version of yourself.
Post-Procedure
Consultations
We provide personalised attention and support for your comfort and recovery. With our expert team by your side, we ensure a smooth journey to renewed confidence, delivering optimal results and satisfaction.
Why Choose MansMatters for E-Shot™ Treatment?
At MansMatters, we specialise in advanced men’s health treatments, offering a higher level of care, expertise and technology than standard clinics.
- Exclusive E-Shot™ processing with an enhanced growth factor method that ensures superior platelet concentration and regenerative benefits.
- Multi-modal treatment approach combining growth factor therapy, shockwave therapy and EMTT for maximum effectiveness.
- Expertise in men’s health, focusing exclusively on male sexual health and delivering specialist treatment plans.
- Free consultations, unlike many clinics that charge £150-£250.
- Discreet and professional care in a private, judgement-free environment where men feel comfortable seeking treatment.
Let's Start Your Journey
to Better Health
Take the first step towards addressing your concerns with complete discretion. Choose between a free
20-minute phone consultation with our medical advisor or visit us for a thorough in-clinic assessment.
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